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People handled with flumazenil really should be monitored for re-sedation, respiratory depression, and other residual benzodiazepine consequences for an proper interval following cure. The prescriber should really concentrate on a danger of seizure in association with flumazenil therapy, specially in long-time period benzodiazepine people and in cyclic antidepressant overdose. The whole flumazenil offer insert should be consulted before use.
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In addition, fatalities are actually described in sufferers who may have overdosed with a mix check here of an individual benzodiazepine, such as alprazolam, and alcohol; Alcoholic beverages amounts viewed in Some sufferers are already lessen than All those normally related to Liquor-induced fatality.
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